Allogic Precision Allergy Centre 研究團隊於國際權威期刊發表多篇過敏診斷與免疫治療領域的高影響力論文,成果聚焦貝類、魚類、甲殼類過敏的分子機制、診斷標記及新型療法開發,持續引領過敏精準醫學研究方向。
- Fung LHT, Yeung HL, Lim CW, Jiang S, Leung NYH, Leung PSC, Leung TF, Wai CYY. Shellfish Allergy Immunotherapy: Are We Moving Forward? Allergies 2025; 5(4): 44.
- Wai CYY, Santos AF, Leung TF, Sampson HA. Novel Strategies for Food Allergy Diagnosis. J Allergy Clin Immuno Pract. 2025 doi: 10.1016/j.jaip.2025.11.022 (online ahead of print). [IF=6.6, rank 4th in field of allergy]
- Lee JZX, Sit JSC, Leung NYH, Chu KH, Leung PSC, Leung TF, Wai CYY. Next Generation Allergen-specific Immunotherapy for Food Allergy. Clinical Rev Allergy Immunol 2025; 68(1):93. [IF=11.3, rank 2nd in field of allergy]
- Li S, Bian J, Xiong Q, Wong BS, Tsui SK, Kwan KM, Leung NYH, Leung TF, Leung PSC, Chu KH, Xiao X, Wai CYY. Revealing the Diverse Allergenic Protein Repertoire of Six Widely Consumed Crab Species: A Species-Specific Allergen in King Crab. Allergy. 2025 Jul 30. doi: 10.1111/all.16674. (epub ahead of print) [IF=12, rank 1st in allergy]
- Wai CYY, Leung NYH, Leung ASY, Tang MF, Marknell-Dewitt A, Rosa-Duque J, Chua G, Yau YS, Chan WH, Ho PK, Kwan MYW, Lee QU, Wong JSC, Lam ICS, Cheng JWCH, Luk DCK, Liu Z, Ngai NA, Chan OM, Leung PSC, Wong GWK, Leung TF. Fish Allergenicity ladder and parvalbumin epitopes for predicting clinical cross-reactivity and reintroduction in Chinese population. Allergy 2025; 80(10): 2810-2823. [IF=12, rank 1st in allergy]
- Liu Z-Y, Wai CYY, Leung ASY, Chan WH, Rosa Duque JS, Lam ICS, Cheng JW, Sit JKC, Ngai NA, Ho PK, Chua GT, Lee QU, Chan OM, Yau YS, Wong JSC, Luk DCK, Ho MHK, Kwan MYW, Tang MF, Leung NYH, Leung TF. Combined Integrative RNA-Seq and Serological sIgE Analysis Enhances Understanding of Fish Allergen Profiles and Diagnostic Strategy for Fish Allergy. Int J Mol Sci. 2024;25(19):10784. [IF=4.9]
- Tong WS, Li S, Leung NYH, Wong WT, Leung TF, Leung PSC, Chu KH, Wai CYY. Shrimp Extract Exacerbates Allergic Immune Responses in Mice: Implications on Clinical Diagnosis of Shellfish Allergy. Clin Rev Allergy Immunol. 2024; 66: (250-259). [IF=11.3, rank 2nd in field of allergy]
- Zheng W, Wai CYY, Sit JKC, Cheng NS, Leung CWM, Leung TF. Routinely Used and Emerging Diagnostic and Immunotherapeutic Approaches for Wheat Allergy. Biomedicines. 2024;12(7):1549. [IF=3.9]
- Li S, Chu KH, Wai CYY. Genomics of Shrimp Allergens and Beyond. Genes. 2023;14(12):2145. [IF=2.8]
- Wai CYY, Leung NY, Leung AS, Fusayasu N, Sato S, Xu KJ, Yau YS, Duque JSR, Kwan MY, Cheng JW. Differential patterns of fish sensitization in Asian populations: implication for precision diagnosis. Allergol Int. 2023; 72(3): 458-465. [IF=6.2]
- Wai CYY, Leung PS. Emerging approaches in the diagnosis and therapy in shellfish allergy. Curr Opin Allergy Clin Immunol. 2022;22(3):202-212. [IF=3.463]
- Wai CYY, Leung NYH, Leung ASY, Ngai SM, Pacharn P, Yau YS, Rosa Duque JSD, Kwan MYW, Jirapongsananuruk O, Chan WH, Chua GT, Lee QU, Piboonpocanun S, Ho PK, Wong JSC, Li S, Xu KJY, Wong GWK, Chu KH, Leung PSC, Vichyanond P, Leung TF. Comprehending the allergen repertoire of shrimp for precision molecular diagnosis of shrimp allergy. Allergy 2022; 77: 3041-3051. [IF=12, rank 1st in allergy]
- Wai CYY, Leung NYH, Leung ASY, Wong GWK, Leung TF. Seafood allergy in Asia: geographical specificity and beyond. Frontiers in Allergy. 2021;2:33. [IF=3.3]
- Wai CYY, Leung NYH, Leung ASY, Shum Y, Leung PS, Chu KH, Kwan YW, Lee QU, Wong JS, Lam IC, Li PF, Xu KJ, Lam CY, Sun JL, Wong GW, Leung TF. Cell-based functional IgE assays are superior to conventional allergy tests for shrimp allergy diagnosis. J Allergy Clin Immunol Pract 2021; 9: 236-44. [IF=6.6, rank 4th in field of allergy]
- Wai CYY, Leung NYH, Chu KH, Leung PS, Leung AS, Wong GW, Leung TF. Overcoming shellfish allergy: How far have we come? Int J Mol Sci. 2020;21(6):2234. [IF=4.9; citation 69]
- Leung NYH, Leung ASY, Xu KJY, Wai CYY, Lam CY, Wong GWK, Leung TF. Molecular and immunological characterization of grass carp (Ctenopharyngodon idella) parvalbumin Cten i 1: A major fish allergen in Hong Kong. Pediatr Allergy Immunol. 2020;31(7):792-804. [IF=4.3; citation 19]
- Wai CYY, Leung NYH, Leung PS, Chu KH. Modulating shrimp tropomyosin-mediated allergy: Hypoallergen DNA vaccines induce regulatory T cells to reduce hypersensitivity in mouse model. Int J Mol Sci. 2019;20(18):4656. [IF=4.9]
- Wai CYY, Leung NYH, Leung PS, Chu KH. Immunotherapy of food allergy: a comprehensive review. Clin Rev Allergy Immunol. 2019;57:55-73. [IF=11.3, rank 2nd in field of allergy]
- Tong WS, Yuen AW, Wai CYY, Leung NYH, Chu KH, Leung PS. Diagnosis of fish and shellfish allergies. J Asthma Allergy. 2018:247-260. [IF=3.7]
- Leung NYH, Wai CYY, Ho MH, Liu R, Lam KS, Wang JJ, Shu SA, Chu KH, Leung PSC. Screening and identification of mimotopes of the major shrimp allergen tropomyosin using one-bead-one-compound peptide libraries. Cell Mol Immunol. 2017;14(3):308-318. [IF=21.8]
- Leung NYH, Wai CYY, Shu SA, Chang CC, Chu KH, Leung PSC. Low-dose allergen-specific immunotherapy induces tolerance in a murine model of shrimp allergy. Int Arch Allergy Immunol. 2017;174(2):86-96. [IF=2.5]
- Wai CYY, Leung NYH, Leung PSC, Chu K. T cell epitope immunotherapy ameliorates allergic responses in a murine model of shrimp allergy. Clin Exp Allergy. 2016;46(3):491-503. [IF=6.3] (Included in the Editor-in-Chief Editorial of Volume 46, Issue 3)
- Leung NYH, Wai CYY, Shu S, Wang J, Kenny TP, Chu KH, Leung PSC. Current immunological and molecular biological perspectives on seafood allergy: a comprehensive review. Clin Rev Allergy Immunol. 2014;46:180-197. [IF=11.3, rank 2nd in field of allergy]
- Wai CYY, Leung NYH, Ho MH, Gershwin LJ, Shu SA, Leung PSC, Chu KH. Immunization with hypoallergens of shrimp allergen tropomyosin inhibits shrimp tropomyosin specific IgE reactivity. PLoS One. 2014;9(11):e111649. [IF=2.9]
- Wai CYY, Leung NYH, Chu KH, Leung PS. From molecule studies of allergens to development of immunotherapy of allergies. J Aller Ther. 2012;3(124):2. [IF=5.15]